GO molecular function ontology term - GO:0046970 - histone H4K16 deacetylase activity, NAD-dependent
Term summary
- ID
- GO:0046970
- Name
- histone H4K16 deacetylase activity, NAD-dependent
- Ontology or CV name
- GO molecular function
- Definition
- Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + NAD+ + H2O = histone H4 L-lysine (position 16) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H4K16 to NAD, producing nicotinamide.
