GO biological process ontology term - GO:0050779 - RNA destabilization
Term summary
ID
GO:0050779
Name
RNA destabilization
Ontology or CV name
GO biological process
Definition
Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.
Parents
is_a
positive regulation of catabolic process
is_a
regulation of RNA stability
is_a
positive regulation of RNA metabolic process
positively_regulates
RNA catabolic process
Annotation
GO biological process
GO:0061158
-
3'-UTR-mediated mRNA destabilization
References:
PMID:31911490
Genes:
rnc1 (SPCC757.09c)
GO:0000290
-
deadenylation-dependent decapping of nuclear-transcribed mRNA
References:
GO_REF:0000024
GO_REF:0000033
PMID:12366830
PMID:15671491
PMID:28031482
Genes:
dcp1 (SPBC3B9.21)
dcp2 (SPAC19A8.12)
lsm1 (SPBC3D6.08c)
nhm1 (SPBP4H10.20)
pdc2 (SPBC19G7.10c)
ste13 (SPBC776.09)
GO:0061157
-
mRNA destabilization
References:
GO_REF:0000033
Genes:
mmi1 (SPCC736.12c)
GO:0060212
-
negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
References:
PMID:39333464
PMID:41184513
Genes:
cid1 (SPAC19D5.03)
ksg1 (SPCC576.15c)
sck1 (SPAC1B9.02c)
GO:0071042
-
nuclear polyadenylation-dependent mRNA catabolic process
References:
GO_REF:0000024
Genes:
csl4 (SPCC1840.11)
cti1 (SPCC1739.07)
dis3 (SPBC26H8.10)
mtr3 (SPBC211.08c)
rrp4 (SPAC2F7.14c)
rrp40 (SPAC22A12.12c)
rrp41 (SPAC3G9.10c)
rrp42 (SPBC16G5.10)
rrp43 (SPBC17D1.03c)
rrp45 (SPCC757.08)
rrp46 (SPBC115.01c)
rrp6 (SPAC1F3.01)
GO:0000288
-
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
References:
GO_REF:0000002
GO_REF:0000024
GO_REF:0000033
Genes:
mpf1 (SPAC4G9.05)
mpf2 (SPCC1682.08c)
puf1 (SPBC56F2.08c)
puf2 (SPBP35G2.14)
puf4 (SPAC6G9.14)
puf5 (SPAC4G8.03c)
sup35 (SPCC584.04)
GO:0000289
-
nuclear-transcribed mRNA poly(A) tail shortening
References:
GO_REF:0000024
GO_REF:0000033
GO_REF:0000111
PMID:19307292
PMID:26804377
PMID:29932902
PMID:30601114
Genes:
caf1 (SPCC18.06c)
ccr4 (SPCC31H12.08c)
mot2 (SPAC16C9.04c)
not1 (SPAC20G8.06)
not11 (SPAC23H4.16c)
not2 (SPCC4G3.15c)
not3 (SPAC1B3.05)
pabp (SPAC57A7.04c)
pan2 (SPAC22G7.04)
pan3 (SPAC1B1.04c)
pan302 (SPBC336.14c)
puf3 (SPAC1687.22c)
rcd1 (SPAC29B12.06c)
vts1 (SPBC13E7.03c)
zfs1 (SPBC1718.07c)
GO:0036450
-
polyuridylation-dependent decapping of nuclear-transcribed mRNA
References:
PMID:19430462
PMID:39333464
Genes:
cid1 (SPAC19D5.03)
GO:1990074
-
polyuridylation-dependent mRNA catabolic process
References:
PMID:23503588
PMID:39333464
Genes:
cid16 (SPAC17H9.01)
dis32 (SPAC2C4.07c)
ski2 (SPCC550.03c)