GO biological process ontology term - GO:0070987 - error-free translesion synthesis
Term summary
- ID
- GO:0070987
- Name
- error-free translesion synthesis
- Ontology or CV name
- GO biological process
- Definition
- The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level.
