GO biological process ontology term - GO:0071596 - ubiquitin-dependent protein catabolic process via the N-end rule pathway
Term summary
- ID
- GO:0071596
- Name
- ubiquitin-dependent protein catabolic process via the N-end rule pathway
- Ontology or CV name
- GO biological process
- Definition
- The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation.
