GO molecular function ontology term - GO:0071885 - N-terminal protein N-methyltransferase activity
Term summary
- ID
- GO:0071885
- Name
- N-terminal protein N-methyltransferase activity
- Ontology or CV name
- GO molecular function
- Definition
- Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.