GO cellular component ontology term - GO:0120513 - 2-(3-amino-3-carboxypropyl)histidine synthase complex
Term summary
- ID
- GO:0120513
- Name
- 2-(3-amino-3-carboxypropyl)histidine synthase complex
- Ontology or CV name
- GO cellular component
- Definition
- A protein complex capable of catalyzing the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the histidine residue of translation elongation factor 2 (EF2), which is the first step in the biosynthesis of diphthamide. The complex is a Dph2 homodimer in archaea and a Dph1-Dph2 heterodimer in eukaryotes.
