GO cellular component ontology term - GO:0180022 - RQC-trigger complex
Term summary
- ID
- GO:0180022
- Name
- RQC-trigger complex
- Ontology or CV name
- GO cellular component
- Definition
- A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B.
