GO cellular component ontology term - GO:1990533 - Dom34-Hbs1 complex
Term summary
- ID
- GO:1990533
- Name
- Dom34-Hbs1 complex
- Ontology or CV name
- GO cellular component
- Definition
- A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.
