PomBase home

Disease association ontology term - MONDO:0005180 - Parkinson disease

Term summary

ID
MONDO:0005180
Name
Parkinson disease
Ontology or CV name
Disease association
Definition
A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression.

Parents

Annotation

Disease association

MONDO:0005180 - Parkinson disease

References:

Genes:

MONDO:0014796 - autosomal recessive early-onset Parkinson disease 23

References:

Genes:

MONDO:0011658 - autosomal recessive early-onset Parkinson disease 7

References:

Genes:

MONDO:0014233 - early-onset Parkinson disease 20

References:

Genes:

MONDO:0011706 - Kufor-Rakeb syndrome

References:

Genes:

MONDO:0008199 - late-onset Parkinson disease

References:

Genes:

MONDO:0013625 - Parkinson disease 17

References:

Genes:

MONDO:0014742 - Parkinson disease 22, autosomal dominant

References:

Genes:

MONDO:0957576 - Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development

References:

Genes: